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"The more complex genomic regulation appears to be, the higher is my allure to shed light on the underlying principles"
Emerging as a modern and aspiring field in 21st century science, noncoding RNAs and their multifaceted regulation of gene transcription and protein translation have yielded new insights into complex diseases such as cancer or obesity.
During my PhD thesis I will concentrate my previous training in mouse transgenics with state-of-the-art techniques in next-generation sequencing and RNA biology to elucidate the impact of long noncoding RNAs on the regulation of hepatic glucose metabolism. As a result of our work the members of the Kornfeld Lab hope to support the invention of novel therapeutics targeting noncoding RNAs in metabolic disorders.